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KMID : 1007420190170030089
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Mood and Emotion
2019 Volume.17 No. 3 p.89 ~ p.98
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Childhood Trauma and Treatment Implications in Major Depressive Disorder in South Korea: Comparison with Medical Outpatients and Two-Year Follow-Up
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Kim Chong-Gi
Jeong Yu-Ri
Kim Eun-Kyung
Park Seon-Cheol
Jo Hwa-Yeon
Kim Dae-Ho
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Abstract
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Background: Little is known about the specific types of childhood trauma and their relationship to treatment-related issues in major depressive disorder (MDD). This study examined trauma experiences and treatment-related variables in outpatients with MDD at a psychiatric department of a university hospital in Korea.
Methods: First, 75 outpatients with MDD were compared to medical outpatients without MDD matched by age, sex, income, and educational qualifications. Both groups completed the Life Stressor Checklist-Revised, which assesses comprehensive life events. Second, treatment-related variables and medication compliance measured by the Compliance Rating Scale were investigated for the two-year period after the initial assessment.
Results: The MDD group had experienced a significantly higher number of lifetime traumas than the control group (p=0.003), including more frequent witnessing of family violence (p<0.001), adulthood physical assault by a family member (p<0.001), and childhood emotional abuse (CEA) (p<0.001). CEA was associated with early onset of the first depressive episode and premature termination of pharmacotherapy; childhood physical neglect was associated with premature termination and less time in therapy.
Conclusion: Our findings support the important influence of childhood emotional trauma and its relationship to treatment retention.
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KEYWORD
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Major depressive disorder, Child abuse, Child neglect, Treatment adherence and compliance, Patient dropouts
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